The pre-tax charge will include costs for severance packages and £32m associated with plant consolidations and closures.
The 2,400 jobs, amounting to 3.4% of its workforce, will go across the board over the next three months.
Xerox's manager for corporate public and media relations, Bill McKee, said the only positions not affected by the cuts would be direct sales. The aim was to return Xerox to a "lean, keen, profitable machine" as soon as possible, he added.
The firm is in talks about the cuts across its global operations with employee representatives.
Xerox is still the subject of an enquiry into its accounting practices by the US Attorney's office.
Story by Andy Scott