Students from Myers Grove City Learning Centre and Stocksbridge High School visited the Heeley site as part of their IT diploma course, which was part of a government initiative to increase work-orientated qualifications launched last year.
The trip included a tour of the factory and talks on item design through to completion, with an emphasis on the role of IT.
Northend's latest purchase, a £1m Heidelberg XL 75 and only the fourth of its kind in the UK, was displayed on the tour.
Proskills' head of marketing and communication Richard Bloxam said: "This is a great example of an employer bringing the school curriculum to life and making school studies more relevant and interesting.
"The ultimate aim is to make people more employable and work-ready when they leave school.
"We want more employers to come forward to link up with schools to make the subject come alive."
Dorothy Betts, HR consultant at Northend, said: "I hope that by opening our doors and showing these students how much IT is an integral part of the day-to-day work we have really brought things to life for them.
"We've always supported initiatives aimed at developing young people's skills and have invited work experience students for many years.
"Print is fascinating – it touches all our lives every day and uses both traditional methods and cutting edge technology."
In October last year, Northend revealed that it was on the acquisition trail after picking up FSC and PEFC accreditations.
Proskills hails Northend over students visit
Proskills has praised the efforts of Sheffield-based printer Northend after it showed local school pupils around its factory in conjunction with the newly launched 14-19 diploma.