A store in Harrow is being fitted out at the moment, which is expected to open in May, and a location for a branch in Reading has been secured.
A further 20 "bolt-on" agreements, which are firms that augment their existing business with a Printing.com franchise, have been signed since the start of the year.
The firm has also turned three stores, Baker Street, Hampstead and Leicester, from owned branches to franchises. The Leicester branch was bought by its management.