The magazine, aimed at girls aged between 10 and 14, is part of a global rollout following a successful launch period in Italy.
Southernprint has printed 100,000 copies of the first issue, which goes on sale on Wednesday at £2.99 and includes a 10-piece Disney stationery set.
The 52-page magazine sits alongside Egmont's other Disney titles that include Disney Princess, Disney & Me, Cars and Toy Story.
Disney UK and Ireland senior publishing manager Siobhan Geraghty said: "We are thrilled to work together with Egmont Magazines to publish DYPU. With Egmont's proven track record of successful Disney launches and the strength of the Disney brand throughout DYOU magazine, we anticipate great excitement both at retail and with girls throughout the UK."
The magazine will be on sale in supermarkets and other retailers.
Egmont to launch Disney magazine in UK
Customer publisher Egmont is to produce Disney's <i>DYOU</i> magazine for its UK launch.