Launched eight years ago and re-launched just last year, Easy Living, which is printed by Wyndeham Roche, is the latest publication to move to an online only model with the July edition set to be its last in print.
Condé Nast cited challenging newsstand conditions and increasing reliance on "multi-bagged" offerings as the reason for its decision.
The tablet and app editions of the title will also be suspended from July although its website, which grew in unique users by 466% in the first quarter of 2013, will continue.
The move puts around 30 jobs at risk, with a consultation currently underway.
A final decision on the future of the print edition and details relating to subscriptions, which account for around a third of its circulation, will be made following the consultation, the publisher said.
Condé Nast Britain managing director Nicholas Coleridge said: "It is a sad decision to have to take, but we see few encouraging signs in this part of the market.
"Easy Living’s print edition has a significant loyal fan base and subscriber base whom we will be reluctant to disappoint, and a particularly talented editorial and publishing staff. However, our digital reach far outweighs that of print, and Easy Living is thriving online."
