Companies are encouraged to enter their best work in six categories that include display graphics, 3D POS and retail interiors.
Closing on 31 July, the lucky winners will be awarded a trip to Las Vegas to visit the SGIA show in October.
According to Inca, the judges will be looking for a combination of "quality, innovation and creativity".
Inca Digital sales and marketing director Heather Kendle said: "We have had some great entries from all over the world so far, encouraged by a multi-level marketing campaign.
"Printers are also unlocking the creative potential in some very unusual substrates. I have a feeling the winning entries this year will excite, inspire and even surprise people."
To enter the Inca Digital Excellence Awards, visit www.incadigital.com/ideas2012.
Winners in the first awards, held in 2010 included Daelprinting from Belgium, Mills Styrox, from Australia, US-based Visual Marketing Systems and America Digitaal Druk, of the Netherlands.
Inca calls for entries to 2012 excellence awards
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Inca is calling for entries to the second iteration of its Inca Digital Excellence Awards, which recognises "stunning" work carried out on the manufacturer's wide-format UV inkjet printers.