Companies are encouraged to enter their best work in six categories that include display graphics, 3D POS and retail interiors.
Closing on 31 July, the lucky winners will be awarded a trip to Las Vegas to visit the SGIA show in October.
According to Inca, the judges will be looking for a combination of "quality, innovation and creativity".
Inca Digital sales and marketing director Heather Kendle said: "We have had some great entries from all over the world so far, encouraged by a multi-level marketing campaign.
"Printers are also unlocking the creative potential in some very unusual substrates. I have a feeling the winning entries this year will excite, inspire and even surprise people."
To enter the Inca Digital Excellence Awards, visit www.incadigital.com/ideas2012.
Winners in the first awards, held in 2010 included Daelprinting from Belgium, Mills Styrox, from Australia, US-based Visual Marketing Systems and America Digitaal Druk, of the Netherlands.
Inca calls for entries to 2012 excellence awards
Inca is calling for entries to the second iteration of its Inca Digital Excellence Awards, which recognises "stunning" work carried out on the manufacturer's wide-format UV inkjet printers.