This was equivalent to $3.35 per diluted share, compared with $1.37 in the 2007 quarter.
Revenue for the quarter came in at $2.79bn, nearly 10% down from $3.09bn in the same three months in 2007. The company generated more than $1bn in cash for 2008 as a whole.
The financial results were announced as RR Donnelley revealed it had been awarded a multi-year $500m deal by the Publishing Group of America.
RR Donnelley president and chief executive Thomas J. Quinlan III said: "Volatility in the global economy has resulted in significant declines in demand across nearly all of the diverse industries that we serve."
He added: "Though our industry has been adversely impacted, we generated over $1bn in cash from operations in 2008. We will continue to focus on two primary elements of our strategy.
"These are to achieve operational excellence in serving our customers and to maintain a very strong liquidity position by maximising cash flow and deploying it prudently."
In January, the company announced it was to raise $400m (£268m) through a debt offering that will be used to meet its short-term debt requirements.
Earlier this month, RR Donnelley said it was set to close its Global Turnkey Solutions site in Limerick, Republic of Ireland, with the loss of nearly 480 jobs.
The company's share price closed around 3% down to $8.64.
RR Donnelley blames declining demand for 482m net loss
RR Donnelley has cited "significant declines in demand" after it recorded a fourth-quarter net loss of $686.9m (482m) from continuing operations, compared to a loss of $292.9m in the same quarter in 2007.
