The £2.50 title will have a daily print run of 3,500 and will retail at around 250 newsagents in the City, the West End, Canary Wharf and Heathrow and London City airports.
The magazine, which is printed alongside the European edition and News Corporation-owned freesheet thelondonpaper, will be distributed to retailers and subscribers before 7am each day.
As previously reported, News Corporation bought The Wall Street Journal last year following a takeover battle for parent company Dow Jones in which Rupert Murdoch paid £2.8bn.
Michael Bergmeijer, Dow Jones' managing director of the consumer media group in Europe, said: "We believe a large number of internationally-minded people living and working in London will value the US edition, and we'll now be able to give them the competitive advantage of having the world's best business paper five hours ahead of US readers."
First Wall Street Journal edition rolls off London presses
The first London-printed copies of the US edition of <i>The Wall Street Journal</i> have rolled off the Man Roland Chromoman presses at Newsfax International's east London print site this morning.
