In its interim management statement, the company said like-for-like sales had grown 19%, with new kit sales up 31% compared with the corresponding period last year.
In its last financial year ending 31 October 2009, the group recorded revenues of £256.1m with pretax profit of £28m.
The group cited Asia as the region of strongest growth, while Europe and the US also showed improved revenues.
Net cash increased to £11.5m in the first four months and the group said it also expected to increase its staff headcount on its newer product developments.
Peter Byrom, chairman of the group, said that, while the year started "positively", the outlook for the company's market remained uncertain.
"After the difficulties of the recent past, we cannot predict with complete confidence how our global customers and suppliers will perform through the balance of the current year," he said. "The board remains confident in the long-term prospects of the group."
Domino said its next trading update would be issued on Monday 21 June.
Domino cautious despite positive start to the year
Domino Printing Sciences has recorded a 19% rise in turnover, year-on-year, for the first four months of its financial year, but warned it could not "predict with complete confidence" its performance for the rest of the financial year.