The £3.5m-turnover company went into administration on Tuesday with administrator Graham Wolloff, of Elwell Watchorn & Saxton, appointed to the firm.
Piggott Black Bear (Cambridge) prints journals, magazines and high-quality corporate and commercial colour print.
It was formed in 2004 following the merger of Piggott Printers and Black Bear Press, which together accumulated more than 180 years of print experience.
However, the business failed in October 2007 and was bought by Philip Colchester, who is currently the managing director of Colchester Print Group.
The failure of Piggott Black Bear (Cambridge) has no bearing on Colchester Print Group, which comprises of Breckland Print, Moreton Hall Press and Norwich Labels.